ea0013oc2 | Steroid synthesis and action | SFEBES2007
Almiro do Vale Isabel
, Egertová Michaela
, Guasti Leonardo
, Elphick Maurice R
, Clark Adrian JL
The melanocortin-2-receptor accessory protein (MRAP) is a type I integral transmembrane protein required for the functional expression of the melanocortin-2-receptor (MC2R).Here we have investigated the expression and biochemical properties of mouse MRAP. Initially, mouse MRAP and MC2R tissue expression were determined by RT-PCR, being only present in the adrenal gland and fat tissue. Then, by in situ hybridisation studies using a full-length MRAP...